REGULATION OF OXIDATIVE ACTIVITY AND DELTA-PSI OF LIVER-MITOCHONDRIA OF ACTIVE AND HIBERNATING GOPHERS - THE ROLE OF PHOSPHOLIPASE-A2

被引：7
作者：
BRUSTOVETSKY, NN
EGOROVA, MV
MAYEVSKY, EI
机构：
[1] Institute of Theoretical and Experimental Biophysics, U.S.S.R. Academy of Sciences, Puschchino
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 102卷 / 03期
关键词：
D O I：
10.1016/0305-0491(92)90059-Z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. In the present work the initially lowered oxidase activity of liver mitochondria of hibernating gophers is shown to increase upon Ca2+-loading, after freezing-thawing repeated three times and after swelling in a medium containing potassium acetate as well as in a hypotonic sucrose medium. 2. In all cases the inhibition of phospholipase A2 hindered the increase of the oxidase activity of mitochondria. 3. Mitochondria of hibernating gophers have a lowered DELTA-PSI in comparison with active animals, which is restored in the hypotonic medium.
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页码：635 / 638
页数：4
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