MORPHOLOGIC ULTRASTRUCTURE OF ANCHORING FIBERS IN NORMAL VOCAL FOLD BASEMENT-MEMBRANE ZONE

被引:42
作者
GRAY, SD
PIGNATARI, SSN
HARDING, P
机构
[1] Department of Otolaryngology, University of Utah, Salt Lake City, UT
[2] Department of Otolaryngology, Escola Paulista De Medicina, Sao Paulo
[3] Department of Otolaryngology, University of Iowa, Iowa City, IA
关键词
ANCHORING FIBERS; VOCAL FOLD; DYSPHONIA;
D O I
10.1016/S0892-1997(05)80318-2
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
Anchoring fibers are collagenous structures that help secure basal cells to the superficial layer of the lamina propria (SLLP). Transmission electron microscopy was used to study the morphology and organization of these anchoring fibers at the human vocal fold basement membrane zone. This study shows that anchoring fibers loop from the lamina densa through the lamina propria and reattach to the lamina densa. Collagen fibers from the lamina propria appear to pass through the loops created by the anchoring fibers. This relationship partially explains how the epidermis secures itself to the SLLP during vibration resulting from phonation. The population density of anchoring fibers and genetics is discussed.
引用
收藏
页码:48 / 52
页数:5
相关论文
共 18 条
  • [1] Sakai, Keene, Morris, Burgeson, Type VII collagen is a major structural component of anchoring fibrils, J Cell Biol, 103, pp. 1577-1586, (1986)
  • [2] Susi, Belt, Kelly, Fine structure of fibrillar complexes associated with the basement membrane in human oral mucosa, J Cell Biol, 34, pp. 686-690, (1967)
  • [3] Laguens, Subepithelial fibrils associated with the basement membrane of human cervical epithelium, Journal of Ultrastructure Research, 54, pp. 202-208, (1972)
  • [4] Bentz, Morris, Murray, Sakay, Hollister, Burgeson, Isolation and partial characterization of a new human collagen with an extended triple-helical structural domain, Proc Natl Acad Sci USA, 80, pp. 3168-3172, (1983)
  • [5] Briggaman, Wheeler, Epidermolysis bullosa dystrophica recessive: a possible role of anchoring fibrils in the pathogenesis, J Invest Dermatol, 65, pp. 203-211, (1975)
  • [6] Tidman, Eady, Evaluation of anchoring fibrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique, J Invest Dermatol, 84, pp. 374-377, (1985)
  • [7] Katz, The epidermal basement membrane zone structure, ontogeny and role in disease, J Am Acad Dermatol, 11, pp. 1025-1037, (1984)
  • [8] Tidman, Eady, Ultrastructural morphometry of normal human dermal-epidermal junction: the influence of age, sex, and body region on laminar and nonlaminar components, J Invest Dermatol, 83, pp. 448-453, (1984)
  • [9] Hirano, Structure of the vocal fold in normal and disease states, ASHA Rep, 11, pp. 11-30, (1981)
  • [10] Hirano, Kurita, Nakashima, Growth, development and aging of human vocal fold, Vocal fold physiology, (1983)