MORPHOLOGY AND PHYSIOLOGY OF SKELETAL-MUSCLE IN AGING RODENTS

被引：167

作者：

CACCIA, MR

HARRIS, JB

JOHNSON, MA

机构：

[1] NEWCASTLE GEN HOSP,REG NEUROL CTR,MUSCULAR DYSTROPHY GRP LAB,NEWCASTLE TYNE NE4 6BE,TYNE & WEAR,ENGLAND

[2] MCMASTER UNIV,DEPT NEUROSCI,HAMILTON L8S 4L8,ONTARIO,CANADA

来源：

MUSCLE & NERVE | 1979年 / 2卷 / 03期

关键词：

D O I：

10.1002/mus.880020308

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Aging in the rodent is accompanied by a progressive loss of skeletal muscle fibers. The muscle twitch also becomes slower, probably as a result of fibertype conversion from “fast‐twitch” to “slow‐twitch.” The loss of muscle fibers precedes signs of obvious weakness and appears to involve the loss of entire functioning motor units. In the mouse, this loss of motor units correlates with a loss of axons from the innervating nerve trunks. Copyright © 1979 Houghton Mifflin Professional Publishers

引用

页码：202 / 212

页数：11

共 25 条

[1]

BALLANTYNE JP, 1975, RECENT ADV MYCOLOGY, P99

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